Eosinophils in innate immunity: an evolving story
Identifieur interne : 000105 ( Main/Exploration ); précédent : 000104; suivant : 000106Eosinophils in innate immunity: an evolving story
Auteurs : Revital Shamri [États-Unis] ; Jason J. Xenakis [États-Unis] ; Lisa A. Spencer [États-Unis]Source :
- Cell and Tissue Research [ 0302-766X ] ; 2011-01-01.
English descriptors
Abstract
Abstract: Eosinophils are innate immune leukocytes found in relatively low numbers within the blood. Terminal effector functions of eosinophils, deriving from their capacity to release their content of tissue-destructive cationic proteins, have historically been considered primary effector mechanisms against specific parasites, and are likewise implicated in tissue damage accompanying allergic responses such as asthma. However, the past decade has seen dramatic advancements in the field of eosinophil immunobiology, revealing eosinophils to also be key participants in many other facets of innate immunity, from bridging innate and adaptive immune responses to orchestrating tissue remodeling events. Here, we review the multifaceted functions of eosinophils in innate immunity that are currently known, and discuss new avenues in this evolving story.
Url:
DOI: 10.1007/s00441-010-1049-6
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000728
- to stream Istex, to step Curation: 000728
- to stream Istex, to step Checkpoint: 000044
- to stream Main, to step Merge: 000106
- to stream Main, to step Curation: 000105
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Eosinophils in innate immunity: an evolving story</title><author><name sortKey="Shamri, Revital" sort="Shamri, Revital" uniqKey="Shamri R" first="Revital" last="Shamri">Revital Shamri</name></author><author><name sortKey="Xenakis, Jason J" sort="Xenakis, Jason J" uniqKey="Xenakis J" first="Jason J." last="Xenakis">Jason J. Xenakis</name></author><author><name sortKey="Spencer, Lisa A" sort="Spencer, Lisa A" uniqKey="Spencer L" first="Lisa A." last="Spencer">Lisa A. Spencer</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:435BF3FD41F0093BFBBBB505627EF7013B8917C3</idno><date when="2010" year="2010">2010</date><idno type="doi">10.1007/s00441-010-1049-6</idno><idno type="url">https://api.istex.fr/document/435BF3FD41F0093BFBBBB505627EF7013B8917C3/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000728</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000728</idno><idno type="wicri:Area/Istex/Curation">000728</idno><idno type="wicri:Area/Istex/Checkpoint">000044</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000044</idno><idno type="wicri:doubleKey">0302-766X:2010:Shamri R:eosinophils:in:innate</idno><idno type="wicri:Area/Main/Merge">000106</idno><idno type="wicri:Area/Main/Curation">000105</idno><idno type="wicri:Area/Main/Exploration">000105</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Eosinophils in innate immunity: an evolving story</title><author><name sortKey="Shamri, Revital" sort="Shamri, Revital" uniqKey="Shamri R" first="Revital" last="Shamri">Revital Shamri</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Allergy and Inflammation, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 02215, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Xenakis, Jason J" sort="Xenakis, Jason J" uniqKey="Xenakis J" first="Jason J." last="Xenakis">Jason J. Xenakis</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Allergy and Inflammation, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 02215, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Spencer, Lisa A" sort="Spencer, Lisa A" uniqKey="Spencer L" first="Lisa A." last="Spencer">Lisa A. Spencer</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Allergy and Inflammation, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 02215, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>330 Brookline Avenue, E/CLS Rm 935, 02215, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="1"><country wicri:rule="url">États-Unis</country></affiliation></author></analytic><monogr></monogr><series><title level="j">Cell and Tissue Research</title><title level="j" type="abbrev">Cell Tissue Res</title><idno type="ISSN">0302-766X</idno><idno type="eISSN">1432-0878</idno><imprint><publisher>Springer-Verlag</publisher><pubPlace>Berlin/Heidelberg</pubPlace><date type="published" when="2011-01-01">2011-01-01</date><biblScope unit="volume">343</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="57">57</biblScope><biblScope unit="page" to="83">83</biblScope></imprint><idno type="ISSN">0302-766X</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0302-766X</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Eosinophil</term><term>Immunomodulation</term><term>Innate immunity</term><term>Piecemeal secretion</term><term>Tissue remodeling</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Eosinophils are innate immune leukocytes found in relatively low numbers within the blood. Terminal effector functions of eosinophils, deriving from their capacity to release their content of tissue-destructive cationic proteins, have historically been considered primary effector mechanisms against specific parasites, and are likewise implicated in tissue damage accompanying allergic responses such as asthma. However, the past decade has seen dramatic advancements in the field of eosinophil immunobiology, revealing eosinophils to also be key participants in many other facets of innate immunity, from bridging innate and adaptive immune responses to orchestrating tissue remodeling events. Here, we review the multifaceted functions of eosinophils in innate immunity that are currently known, and discuss new avenues in this evolving story.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Massachusetts</li></region></list><tree><country name="États-Unis"><region name="Massachusetts"><name sortKey="Shamri, Revital" sort="Shamri, Revital" uniqKey="Shamri R" first="Revital" last="Shamri">Revital Shamri</name></region><name sortKey="Spencer, Lisa A" sort="Spencer, Lisa A" uniqKey="Spencer L" first="Lisa A." last="Spencer">Lisa A. Spencer</name><name sortKey="Spencer, Lisa A" sort="Spencer, Lisa A" uniqKey="Spencer L" first="Lisa A." last="Spencer">Lisa A. Spencer</name><name sortKey="Spencer, Lisa A" sort="Spencer, Lisa A" uniqKey="Spencer L" first="Lisa A." last="Spencer">Lisa A. Spencer</name><name sortKey="Xenakis, Jason J" sort="Xenakis, Jason J" uniqKey="Xenakis J" first="Jason J." last="Xenakis">Jason J. Xenakis</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Musique/explor/XenakisV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000105 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000105 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Musique
|area= XenakisV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:435BF3FD41F0093BFBBBB505627EF7013B8917C3
|texte= Eosinophils in innate immunity: an evolving story
}}
| This area was generated with Dilib version V0.6.33. |  |